Lichen Simplex Chronicus (LSC) is a widespread dermatological condition characterized by skin lichenification due to persistent scratching, predominantly affecting adults with a slight female predisposition. The exact pathogenesis of LSC remains unclear, but it is associated with skin barrier disorders and psychological factors, notably stress, which exacerbate pruritus. While LSC is not life-threatening, it imposes a significant psychosocial burden, impacting patients' quality of life (QoL). Studies have shown that LSC patients often struggle with social skills, interpersonal relationships, sleep disturbances, and sexual dysfunction. The World Health Organization's QoL definition serves as the study's theoretical framework, encompassing individuals' perceptions of their life in the context of culture, health, psychological well-being, social relationships, and environment. Understanding the multifaceted impact of LSC on patients' QoL is crucial for comprehensive care and management.
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